Genotype Frequency to Phenotype Probability Calculator

Genotype Frequency to Phenotype Probability Calculator

How to Use This Tool:

This tool helps calculate the probability of different phenotypes based on the frequencies of the three possible genotypes (AA, Aa, aa) for a single gene with two alleles (A and a).

Input Frequencies:

  • Enter the percentage frequency for each genotype: AA, Aa, and aa.
  • The sum of these three frequencies **must** be 100%. The tool will validate this.

Dominance Pattern:

  • Complete Dominance: If allele 'A' is completely dominant over 'a', then individuals with genotypes 'AA' and 'Aa' will express the same dominant phenotype. Only 'aa' individuals will express the recessive phenotype.
  • Incomplete Dominance / Codominance: In these cases, each genotype (AA, Aa, aa) results in a distinct phenotype. For example, in incomplete dominance, 'Aa' might show an intermediate phenotype. In codominance, both 'A' and 'a' might be expressed simultaneously (e.g., blood types).

Calculation Logic:

  • Complete Dominance:
    • Probability of Dominant Phenotype: Frequency(AA) + Frequency(Aa)
    • Probability of Recessive Phenotype: Frequency(aa)
  • Incomplete Dominance / Codominance:
    • Probability of Phenotype for AA: Frequency(AA)
    • Probability of Phenotype for Aa: Frequency(Aa)
    • Probability of Phenotype for aa: Frequency(aa)

**Disclaimer:** This tool is for **educational and conceptual understanding only**. It uses simplified Mendelian inheritance principles for demonstration. It is **NOT** intended for actual genetic analysis, medical diagnosis, or any real-world scientific or health decision-making. Real genetic traits can be influenced by multiple genes, environmental factors, and complex interactions not accounted for here. For accurate genetic analysis, please consult qualified geneticists or healthcare professionals.

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